Quality of life and survival rate in patients with bone tumors
Abstract
Studying quality of life and its factors as well as the impact of quality of life on the outcomes of treatment and postoperative rehabilitation is important due to significant progress in the treatment of patients with primary and metastatic bone tumor. This study continues series of works of the authors in this area. The study is devoted to reveal relationship between the main parameters of quality of life and survival in patients with bone tumors. The data of psychological study in 50 patients with bone tumors were compiled. The EORTC QLQ-C30 (Quality of Life Questionnaire Core-30) and BM-22 (additional module) were used to study the main parameters of quality of life. Patient survival was calculated using Kaplan-Meier method. According the results, higher quality of life among patients with bone tumors correlates with better survival, while decreased quality of life in patients, manifested in the somatization of negative emotional experiences, is associated with a lower level of survival. In accordance with the results obtained in the framework of a multidisciplinary approach to the treatment and rehabilitation of patients with bone tumors, the main directions of psychological assistance in the oncoortopedic clinic are done.
About the Authors
E. B. Usmanova
Saint Petersburg State University
Russian Federation
Russian Federation
O. Yu. Shchelkova
Saint Petersburg State University
Russian Federation
Russian Federation
E. A. Sushentsov
FSBI «N.N. Blokhin national medical research center of oncology» of the Ministry of Health of Russia
Russian Federation
Russian Federation
D. I. Sofronov
FSBI «N.N. Blokhin national medical research center of oncology» of the Ministry of Health of Russia
Russian Federation
Russian Federation
A. K. Valiev
FSBI «N.N. Blokhin national medical research center of oncology» of the Ministry of Health of Russia
Russian Federation
Russian Federation
References
1. Aaronson NK, Ahrnedzai S, Bergrnan B. The European Organisation for Research and Treatrnent of Cancer QLQ-C30: A quality of life instrurnent for use in international clinical trilas in oncology. Journal of National Cancer lnstitute. 1993;85:365-375.
2. Bekkering WP, Vlieland TP, Kooprnan HM. Quality of life in young patients after bone turnor surgery around the knee joint and cornparison with healthy controls. Pediatric Blood Cancer. 2010;54(5):738-745.
3. Сella DF, Fairclough D, Bonorni P et al. Quality of life in advance non-srnall cell lung cancer: results frorn Eastern Cooperative Oncology Group Study 5592. Proc. ASCO. 1997:100-110.
4. Coates AS, Gebski V, Signorini D et al. For the Australian New Zealand Breast Cancer Trials Group. Prognostic value of quality of life scores during chernotherapy for advanced breast cancer. J Clin Oncol. 1992;10:1833-1838.
5. Fayers P, Aarson N, Bjordal K, Sullivan M. QLQ C-30 Scoring Manual. EORTC Study Group on Quality of Life. Brussels. 1995.
6. Klaff R, Berglund A, Varenhorst E. Clinical characteristics and quality-of-life in patients surviving a decade of prostate cancer with bone rnetastases. BJU Int. 2015;117(6):904-913.
7. Mason GE, Aung L, Gall S, Meyers PA, Butler R, Krug S, Kirn M, Healey JH, Gorlick R. Quality of life following arn-putation or lirnb preservation in patients with lower extrernity bone sarcorna. Front Oncol. 2013;14:203-210.
8. Morishige M, Murarnatsu K, Torninaga Y. Surgical treatrnent of rnetastatic fernoral fractures: achieving an irnproved quality of life for cancer patients. Anticancer Res. 2015;35(1):427-432.
9. Paredes T Pereira M, Moreira H, Sirnoes MR, Canavarro MC. Quality of life of sarcorna patients frorn diagnosis to treatrnents: predictors and longitudinal trajectories. Eur J Oncol Nurs. 2011;15(5):492-499.
10. Perisano C, Scararnuzzo L, De Santis V. Quality of life following surgical treatrnent of lower lirnb rnetastases in long bone. J Biol Regul Horneost Agents. 2015;29(2):501-507.
11. Алиев МД, Сушенцов ЕА. Современная онкоортопедия. Саркомы костей, мягких тканей и опухоли кожи. 2012;4:3-10.
12. Вассерман ЛИ, Трифонова ЕА. Методология исследования связанного со здоровьем качества жизни. Психологическая диагностика расстройств эмоциональной сферы и личности. 2014:30-43.
13. Новик АА, Ионова ТИ. Руководство по исследованию качества жизни в медицине. 2-е изд. Под ред. акад. РАМН Ю.Л. Шевченко. 2007.
14. Семиглазова ТЮ и соавт. Качество жизни - важнейший критерий эффективности лечения и реабилитации онкологических больных. Онкопсихология. Руководство. Ред. А.М. Беляев, В.А. Чулкова, ТЮ. Семиглазова, М.В. Рогачев. Гл. 1. 2017:10-32.
15. Тарабрина НВ, Ворона ОА, Курчакова МС и соавт. Онкопсихология. М.: Институт психологии РАН. 2010.
16. Усманова ЕБ, Сушенцов ЕА, Щелкова ОЮ. Качество жизни пациентов с опухолями костей. Саркомы костей, мягких тканей и опухоли кожи. 2015;1:55-61.
17. Щелкова ОЮ, Усманова ЕБ. Качество жизни и психологические характеристики больных с опухолевым поражением костей. Вестник Санкт-Петербургского университета. 2015;64-76.
18. Щелкова ОЮ, Сушенцов ЕА, Усманова ЕБ, Валиев АК, Горбунов ИА. Качество жизни и психологические факторы восприятия боли при опухолевом поражении костей. Саркомы костей, мягких тканей и опухоли кожи. 2018;3:31-35.
Review
For citations:
Usmanova E.B., Shchelkova O.Yu., Sushentsov E.A., Sofronov D.I., Valiev A.K. Quality of life and survival rate in patients with bone tumors. Bone and soft tissue sarcomas, tumors of the skin. 2019;11(2):34-39. (In Russ.)
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