Algorithm of treatment tactic of cancer patients with infection of endoprosthesis
Abstract
Most infectious complications in the bed of the implant are due to colonization of methicillin-resistant flora and are very difficult and high material costs for treatment. More than 50% of infectious complications occur during the first 14 days after the implantation. There are several treatments, which include a mandatory component - the antibiotic therapy. The main goals of surgical treatment of infectious complications are preventing mortality in this group of patients and limb salvage. The scheme of diagnosis and treatment based on evidence of etiological factors, pathogenesis of complications, risk factors contributing to their development and data on the stability of the prosthesis, the indicators of aspirate and of time after surgery. So far a holistic approach to the therapy is not developed because of lack of data and prospective, randomized clinical trials. Our study proposes a new algorithm for the diagnosis and treatment of infectious complications after joint replacement.
About the Authors
D. V. Nisichenko
N.N. Blokhin R ussian C ancer R esearch C enter, R ussian Academy of M edical S ciences
Russian Federation
Russian Federation
N. V. Dmitrieva
N.N. Blokhin R ussian C ancer R esearch C enter, R ussian Academy of M edical S ciences
Russian Federation
Russian Federation
I. N. Petukhova
N.N. Blokhin R ussian C ancer R esearch C enter, R ussian Academy of M edical S ciences
Russian Federation
Russian Federation
V. A. Sokolovskiy
N.N. Blokhin R ussian C ancer R esearch C enter, R ussian Academy of M edical S ciences
Russian Federation
Russian Federation
Е. R. Senzhapova
N.N. Blokhin R ussian C ancer R esearch C enter, R ussian Academy of M edical S ciences
Russian Federation
Russian Federation
М. S. Кubirov
N.N. Blokhin R ussian C ancer R esearch C enter, R ussian Academy of M edical S ciences
Russian Federation
Russian Federation
Z. V. Grigoryevskaya
N.N. Blokhin R ussian C ancer R esearch C enter, R ussian Academy of M edical S ciences
Russian Federation
Russian Federation
М. D. Aliev
N.N. Blokhin R ussian C ancer R esearch C enter, R ussian Academy of M edical S ciences
Russian Federation
Russian Federation
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Review
For citations:
Nisichenko D.V., Dmitrieva N.V., Petukhova I.N., Sokolovskiy V.A., Senzhapova Е.R., Кubirov М.S., Grigoryevskaya Z.V., Aliev М.D. Algorithm of treatment tactic of cancer patients with infection of endoprosthesis. Bone and soft tissue sarcomas, tumors of the skin. 2011;(2):12-34. (In Russ.)
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