Askin tumor (clinical information, clinical case of long-term follow-up of patient after the combined treatment)
Abstract
Askin tumor or malignant small cell thoracopulmonary tumor is extremely rare, practically is isolated incident, it is characterized with extreme malignancy and unsatisfactory treatment results due to difficulties in diagnostics and late detection. This paper presents a clinical case of prolonged observation of a patient with Ewing's sarcoma of the second rib with metastasis in the right lung after nonradical treatment at the place of residence. Combination treatment with an emphasis on radiation therapy was carried out at the Medical Radiological Scientific Center. Patient was treated and maintained her high quality of life. The patient is being observed for 18 years, she graduated from the university, working.
About the Author
V. N. HmelevskayaRussian Federation
249036, Obninsk, Koroliova str., 4.
References
1. Askin FB, Rosa J, Sibley RK, Dehner LR, McAlisher WH. Malignant small cell tumor of thoracopulmonary region in childhood. А distinctiye clinicopathologic entity of uncertain histogenesis. Cancer. 1979;43:2438-245.
2. Bernstain М, Kovar Н, Paulussen М, Lor Randall R, Schuck А, Teot L, Juergens Н. Ewing's sarcoma family oftumors: current managmant. The Oncologist. 2006;(11):503-519.
3. Carvajal R, Meyers Р. Ewing's sarcoma and primitive neuro-ectodeimal family oftumrns. Hematol Oncol Clin Norht Am. 2005;(19):501-525.
4. Grubb MR, Currier BL, Pritchaid DJ, Ebersold MJ. Primary Ewing's sarcoma of the spine. 1994;19(3):309-313.
5. Mozel RP, Davis MJ, Gilkey FW, Kransdorf M, Rosado de Christenson ML, Kumar R. Primary Ewing's sarcoma of rib. Radiographics. 1990;106(5):899-914.
6. Shamberger RC, Laquaglia МР, Krailo MD, Miser JS, Pritchaid DJ, Gebhardt МС. Ewing sarcoma of the rib: results of an intergroup study with analysis of outcome Ьу timing of resection. J Thorae Cardiovasc Surg. 2000;19(6):1154-1161.
7. Ivanova NM. The features of treatment of children with tumors of the family of sarcoma of Ewing of а chest wall relating to group of high risk. The RONTs bulletin of N.N. Blochin of the Russian Academy of Medical Science. 2009;20(3) (In Russ.).
8. Ozaki Т, Hillman А, Hoffman С, Rodl R, Blasius S, Link Т. Significance of surgical margin on the prognosis of patients with Ewing's sarcoma. Сапсег. 1996;(78):892-900.
9. Saenz N, Hass D, Meyeis Р, Wollner N, Gollamudi S, Bains L. Pediatric chest wall Ewing's sarcoma. Ped Surg. 2000;35(4):550-555.
10. Rao В, Ann Haves F, Thompson EI, Kumar АР, Fleming ID, Green АА. Chest wall resection for Ewing's sarcoma of the rib: an unnecessary procedure. Ann Thorac Surg. 1988;46:40-44.
11. Paulussen М, Ahrens S, Burdach S, Craft А, Dockhorn-Dwor-niczak, Dunst В. Primary metastatic (stage Ewing tumor: survival and IV) analysis of 171 patients from the EICESS studies. Ann Oncol. 1998;9(3):275-281.
12. Kolb EA, Kushner BN, Gorlick R. Long-term event-free survival after intensive chemotherapy for Ewing's family of tumors in children and young adults. J Clin Oncol. 2003;21:3423-3430.
13. Osnowi klinicheskoi radlobiologii. Pod red. M.S. Dzhotsner and O.J. van der Kogel's edition. 2013 (In Russ.).
14. Nesbit МЕ, Gehan EA, Burgert ЕО, Vietti TJ; Cangir A, Tefft М. Multimodal therapy for the management of primary nonmetastatic Ewing's sarcoma of bone. J Clin Oncol. 1990;8(10):1664-1674.
15. Kiselyov LP, Aleynikova OV The localized forms of tumors of family of sarcoma of Ewing in Republic of Belarus: The analysis of clinical outcomes at 115 patients for the 15-year period of observation. Onkopediatriya. 2016;3(3):182-187.
16. Kaprin AD, Galkin VN, Zhavoronkov LP, Ivanov VK, Ivanov SA, Romanko YuS. Synthesis of basic and applied research is Ше basis of obtaining high-quality findings iind translating them into clinical practice. Radiation and risk. 2017;26(2):26-40.
17. Kaprin AD, Mardinskiy YS, Smirnov VP, Ivanov SA, Kostin AA, Polikhov SA, Reshetov IV, Fatianova AS, Denisenko MV, Epatova TV, Korenev SV, Tereshchenko AV, Filonenko EV, Gafarov ММ, Romanko YS. The history of radiation therapy (part I). Biomedical Photonics. 2019;8(1):52-62.
Review
For citations:
Hmelevskaya V.N. Askin tumor (clinical information, clinical case of long-term follow-up of patient after the combined treatment). Bone and soft tissue sarcomas, tumors of the skin. 2019;11(3):57-62. (In Russ.)