Modern criteria for assessing the therapeutic pathomorphosis of synovial sarcoma: clinical significance and outcome prediction
https://doi.org/10.17650/2219-4614-2025-17-2-73-82
Abstract
Synovial sarcoma is a rare malignant soft tissue tumor characterized by high aggressiveness and a propensity for metastasis. The assessment of therapeutic pathomorphosis plays a crucial role in predicting disease outcomes and selecting the optimal treatment strategy. This article discusses the morphological and molecular characteristics of synovial sarcoma, existing classifications of pathomorphosis, modern assessment methods, and the prognostic significance of pathomorphosis degree.
Special attention is given to the impact of various factors on treatment efficacy, the prospects of personalized medicine, and the integration of innovative technologies in the diagnosis and management of this tumor.
About the Authors
D. R. MakhachevRussian Federation
1 Ostrovityanova St., Moscow 117513,
D. V. Bulanov
Russian Federation
1 Ostrovityanova St., Moscow 117513,
D. M. Ametov
Russian Federation
1 Ostrovityanova St., Moscow 117513,
M. O. Abakarov
Russian Federation
1 Ostrovityanova St., Moscow 117513,
A. R. Abacharaeva
Russian Federation
1 Ostrovityanova St., Moscow 117513,
P. A. Bagandova
Russian Federation
1 Ostrovityanova St., Moscow 117513,
R. M. Gabibullaev
Russian Federation
1 Ostrovityanova St., Moscow 117513,
A. D. Dzhanboriev
Russian Federation
10 Studencheskaya St., Voronezh 394036
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Review
For citations:
Makhachev D.R., Bulanov D.V., Ametov D.M., Abakarov M.O., Abacharaeva A.R., Bagandova P.A., Gabibullaev R.M., Dzhanboriev A.D. Modern criteria for assessing the therapeutic pathomorphosis of synovial sarcoma: clinical significance and outcome prediction. Bone and soft tissue sarcomas, tumors of the skin. 2025;17(2):73-82. (In Russ.) https://doi.org/10.17650/2219-4614-2025-17-2-73-82