Pelvic ewing’s sarcoma (Literary reference. The clinical case: long-term follow-up of treated pelvic Ewing’s sarcoma with metastases in regional lymph nodes and lung)

Abstract

One of the characteristics of pelvic Ewing’s sarcoma is its ability to spread to healthy pelvic bones. Pelvic Ewing’s sarcoma is generally a late diagnosis due to lack of pathognomonic signs and symptoms. The majority of diagnosed cases are advanced with big size of tumor spread to two or even three pelvic bones often with distant metastases. Most patients are treated with chemoradiotherapy: half of pelvis is exposed to radiation with total radiation dose of 55-60 Gy which leads to severe radiation injuries of soft tissues and pelvic bones. Radiation boost led to significant decrease of radiation injuries. Due to high frequency of lung metastases preventive wide-field radiation therapy is used although treatment with total radiation dose of 12 Gy didn’t lead to long-term result improvement. Increase to 20 Gy resulted in total absence of lung metastases which significantly improved long-term results, 10-year survival rate was 62.5%. In the paper we provide information of modern treatment methods and report clinical case.