Ultrasound diagnostics of utrerus leiomyosarcoma metastases
Abstract
Material of the research were the results of the survey of 37 patients with uterus leiomyosarcoma (LMS), who were treated and observed at federal state scientific institution «Russian Cancer Research Center them. Blokhin» in the period from 2012 to 2014. Sonographic signs of metastases and recurrent uterus LMS are mostly hypoechogenic – the same as the signs of primary tumor. Echographic diagnostics makes possible to detect the presence of a pathological process, its localization, structure and sizes of tumor, clarify the diagnosis.
About the Authors
I. K. Mnatsakanyan
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
M. A. Chekalova
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
N. I. Lasareva
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
A. A. Fedenko
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
References
1. D. Angelo E., Prat J. Uterine sarcomas: a review. Gynecol Oncol. 2010, v. 74, p. 131-139.
2. Harlow B.L., Weiss N.S., Lofton S. The epidemiology of sarcomas of the uterus. J. Natl. Cancer Inst. 1986, v. 74, p. 399-402.
3. El-Khalfaoui K., du BoisA., HeitzF., Kurzeder C., Sehouli J., Harter P. Current and future options in the management and treatment of uterine sarcoma. Ther. Adv. Med. Oncol. 2014, v. 6 (1), p. 21-28.
4. Amant F., Moerman P., Neven P. et al. Endometrial cancer. Lancet. 2005, v. 74, p. 491-505.
5. Leibsohn S., d’Ablaing G., Mischell D.R. Jr, Schlaertb J.B. Leiomyosarcoma in a series of hysterectomies performed for presumed uterine leiomyomas. Am. J. Obstet. Gynecol. 1990, v. 162, p. 968-974.
6. Sandruck J.L., Escobar P., Lurain J., Fishman D. Uterine leiomyosarcoma metastatic to the sphenoid sinus: a case report and review of the literature.Gyn Oncol 2004 Feb, v. 92:(2) p. 701-704.
7. Harter P., El-Khalfaoui K., Heitz F., A. du Bois. Operative and Conservative Treatment of Uterine Sarcomas. Маrt 2014.
8. Чекалова М.А. Ультразвуковая диагностика злокачественных новообразований матки. Дисс. д-ра мед. наук. М., 1998, с. 165.
9. Major F.J., Blessing J.A. Silverberg S.G. et al. Prognostic factors in early-stage uterine sarcoma. Cancer. 1993, v. 71, p. 1702-1709.
10. Larson B., Silfversward C., et al. Prognostic factors in uterine leiomyosarcoma. A clinical and histopathological study of 143 cases. The Radiumhemmet series 1936-1981. Acta Oncol. 1990, v. 29, p. 185-191.
11. Nordal R.R., Kristensen G.B., Kaern J., Stenwig A.E., Pettersen E.O., Trope C.G. The prognostic significance of stage, tumor size, cellular atypia and DNA ploidy in uterine leiomyosarcoma. Acta Oncol. 1995, v. 34, p. 797-802.
12. Pautier P., Genestie C., Rey A., Morice P., Roche B., Lhomme C. et al. Analysis of clinicopathologic prognostic factors for 157 uterine sarcomas and evaluation of a grading score validated for soft tissue sarcoma. Cancer (Phila). 2000, v. 88 (6), p. 1425-1431.
13. Лазарева Н.И. Злокачественные мезенхимальные опухоли женских половых органов (клиника, диагностика, лечение, факторы прогноза). Дисс. д-ра мед. наук. М., 2000.
14. Park J.Y., Park S.K., Kim D.Y. et al. The impact of tumor morcellation during surgery on the outcomes of patients with apparently early low-grade endometrial stromal sarcomas of the uterus. Ann Surg Oncol 2011. Nov v. 18 (12): p. 3453-3461.
15. Saiz A.D., Sachdev U., Brodman M.L., Deligdisch L. Metastatic uterine leiomyosarcoma presenting as a primary sarcoma of the parotid gland. Obstet. Gynecol. 1998, v. 92, p. 667-668.
16. Leath C.A., Huh W.K., Straughn J.M. Jr., Conner M.G. Uterine leiomyosarcoma metastatic to the thyroid. Obstet. Gynecol. 2002, v. 100, p. 1122-1124.
17. Pappa L.L., Zagorianakou N., Kitsiou E., Sintou-Mantela E., Bafa M., Malamnou-Mitsi V. Breast metastasis from uterine leiomyosarcoma diagnosed by fine needle aspiration: a case report. On the prognosis of patients with apparently early uterine leiomyosarcoma. Gynecol. Oncol. 2011. Feb 93:(2).
18. Iwamoto I., Fujino T., Higashi Y., Tsuji T., Nakamura N., KomokataT., DouchiT. Metastasis of uterine leiomyosarcoma to the pancreas. J. Obstet. Gynaecol. Res. 2005, v. 31 (6), p. 531-534.
19. Martin J.L., Boak J.G. Cardiac metastasis from uterine leiomyosarcoma. J. Am. Coll. Cardiol. 1983, v. 2, p. 383-386.
20. O’Brien J.M., Brennan D.D., Taylor D.H., Holloway D.P., Hurson B., O’Keane J.C., Eustace S.J. Skeletal muscle metastasis from uterine leiomyosarcoma. Skeletal. Radiol. 2004, v. 33, p. 655-659.
Review
For citations:
Mnatsakanyan I.K., Chekalova M.A., Lasareva N.I., Fedenko A.A. Ultrasound diagnostics of utrerus leiomyosarcoma metastases. Bone and soft tissue sarcomas, tumors of the skin. 2014;(3-4):37-43. (In Russ.)
Views:
77
Email this article 
