Fibrous dysplasia
Abstract
The review of the literature is devoted to the classification, epidemiology, clinical presentation and radiological findings of fibrous dysplasia of the skeleton. fibrous dysplasia (FD) is a benign process of the skeleton that develops in childhood. The clinical presentation of FD is largely determined by the lesion localization and its extent in the skeleton. Small size fibrous dysplasia may be asymptomatic and revealed as an accidental finding. In some cases radiological presentation of FD is similar to benign bone tumors resulting in difficulties of the differential diagnosis of these processes.
About the Authors
A. V. Fedorova
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
I. I. Barna
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
A. B. Bludov
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
A. S. Nered
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
Ya. A. Zamogilnaya
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
N. V. Kochergina
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
References
1. Нейштадт Э.Л., МаркочевА.Б. Опухоли и опухолеподобные заболевания костей. 2007, с. 243-249.
2. Кочергина Н.В. Лучевая диагностика опухолей и опухолеподобных поражений костей и мягких тканей. Практическое руководство. 2005, с. 35-39.
3. Chong V.F., Khoo J.B., Fan Y.F. Fibrous dysplasia involving the base of skull. AJR. 2002, v. 178 (3), p. 717-720.
4. Fitzpatrick K.A., Taljanovic M.S., Speer D.P. et al. Imaging findings of fibrous dysplasia with histopathologic and intraoperative correlation. AJR. 2004, v. 182 (6), p. 1389-1398.
5. Christopher D.M. Fletcher, K. Krishnan Unni, Fredrik Mertens. Tumors of soft tissue and bone. Pathology and Genetics. World Health Organization Classification of Tumours. 2002, p. 341-342.
6. Kransdorf M., Moser R. Jr., Gilkey F. Fibrous dysplasia. Radiographics. 1990, v. 10, p. 519-537.
7. Dorfman H., Czerniak B. Bone tumors. Mosby, St. Louis. 1998.
8. Henry A. Monostotic fibrous dysplasia. J. Bone Joint. Surg. Br. 1969, v. 51, p. 300-306.
9. Harris W.H., Dudley R., Barry R.J. The natural history of fibrous dysplasia: an orthopaedic, pathological, and roentgenographic study. J. Bone Joint. Surg. 1962, v. 44, p. 207-233.
10. Ruggieri P., Sim F., Bond J. et al. Malignancies in fibrous dysplasia. Cancer. 1994, v. 73, p. 1411-1424.
11. Schwartz D., Alpert M. The malignant transformation of fibrous dysplasia. Am. J. Med. Sci. 1964, v. 247, p. 1-20.
12. Yabut S., Kenan S., Sissons H. et al. Malignant transformation of fibrous dysplasia: a case report and review of the literature. Clin. Orthop. Relat. Research. 1988, v. 228, p. 281-289.
13. Bahk W., Kang Y., Rhee S. et al. Cystic fibrous dysplasia in the long bone. Orthopedics. 2007, v. 30, p. 871-873.
14. Dorfman H., Ishida T., Tsuneyoshi M. Exophytic variant of fibrous dysplasia (fibrous dysplasia protuberans). Hum. Pathol. 1994, v. 25, p. 1234-1237.
15. Johns W.D., Gupta S.M., Kayani N. Scintigraphic evaluation of polyostotic fibrous dysplasia. Clin. Nucl. Med. 1987, v. 12, p. 627-631.
Review
For citations:
Fedorova A.V., Barna I.I., Bludov A.B., Nered A.S., Zamogilnaya Ya.A., Kochergina N.V. Fibrous dysplasia. Bone and soft tissue sarcomas, tumors of the skin. 2014;(3-4):3-11. (In Russ.)
Views:
175
Email this article 
