Functional results and follow – up after the local treatment of the breast cancer metastases to the spinal column
Abstract
Breast cancer is the most frequent oncological disease among women. It has especial predisposition for the bone metastatic disease and in 70% of cases the metastases to the spinal column can be found. It is a vital importance problem, because it can lead to such complications, as pathological fractures, pain syndrome, neurological deficits because of the compression of the spinal cord by the bone fragments. These complications can result in invalidization.
On the basis of the statistical analysis group of 76 patients was evaluated for functional results and follow – up of different types of the local treatment of the breast cancer metastases to the spinal column.
About the Authors
E. R. Musaev
N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
A. M. Stepanova
N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
S. L. Gutorov
N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
A. K. Valiev
N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
K. A. Borzov
N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
A. V. Kulaga
N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
A. S. Nered
N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
M. D. Aliyev
N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
Moscow
References
1. Mazeron J.J., Lang P., Simon J.M. et al. New devices inradiation oncology. Bull. Cancer. 2009, v. 94 (9486), p. 109-113.
2. Coleman R.E. Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin. Cancer Res. 2006, v. 12 (20 Pt. 2), p. 6243-6249.
3. Bob T.Li, Matthew H. et al. Treatment and Prevention of Bone Metastases from Breast Cancer: A Comprehensive Review of Evidence for Clinical Practice. J. Clin. Med. 2014, v. 3, p. 1-24.
4. Jensen A., Jacobsen J.B. et al. Incidence of bone metastases and skeletal-related events in breast cancer patients: a population-based cohort study in Denmark. BMC Cancer. 2011, v. 24, p. 29.
5. Chow E., Finkelstein J.A., Sahgal A., Coleman R.E. Metastatic cancer to the bone. In: De VitaV.T., LawrenceT.S., Rosenberg S.A., eds. De Vita, Hellman, and Rosenberg’s Cancer: Principles& Practice of Oncology. 9th ed. Philadelphia, Pa: Lippincott Williams & Wilkins. 2011, p. 2192-2204.
6. Kuchuka М., Hutton B., Morettoa P. et al. Incidence, consequences and treatment of bone metastases in breast cancer patients—Experience from a single cancer centre. Journal of Bone Oncology. 2013, v. 2, Issue 4, p. 137-144.
7. Niikura N., Jun Liu, Naoki Hayashi et al. Treatment Outcome and Prognostic Factors for Patients with Bone-Only Metastases of Breast Cancer: A Single-Institution Retrospective Analysis. The Oncologist. 2011, v. 16, No. 2, p. 155-164.
8. Coleman R.E., Holen I. Bone metastasis. In: Niederhuber J.E., Armitage J.O., Doroshow J.H., Kastan M.B., Tepper J.E., eds. Abeloff’s Clinical Oncology. 5th ed. Philadelphia, Pa: Elsevier. 2014, p. 739-763.
9. Rades D., Veninga T., Lukas J.A. Stalpers, et al. Prognostic factors for local control and survival after radiotherapy of metastatic spinal cord compression. Journal of clinical oncology. 2011, v. 24, No. 21, p. 3388-3393.
10. Ibrahim A., Crockard A., Antonietti P. et al. Does spinal surgery improve the quality of life for those with extradural (spinal) osseous metastases? An international multicenter prospective observational study of 223 patients. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2007. J. Neurosurg. Spine. 2012, v. 8 (3), p. 271-278.
Review
For citations:
Musaev E.R., Stepanova A.M., Gutorov S.L., Valiev A.K., Borzov K.A., Kulaga A.V., Nered A.S., Aliyev M.D. Functional results and follow – up after the local treatment of the breast cancer metastases to the spinal column. Bone and soft tissue sarcomas, tumors of the skin. 2015;(3):12-18. (In Russ.)
Views:
83
Email this article 
