Модификация режимов химиотерапии сарком мягких тканей. Старые препараты и новые возможности
Аннотация
Проведен сравнительный анализ эффективности лечения 78 больных СМТ, получавших высокодозную химиотерапию режимом HD AI и 50 больных ретроспективно проходивших терапию режимом MAID. Отмечено увеличение ВБП на 44% в высокодозной группе с 5 до 7,2 месяцев и увеличение общей выживаемости с 10 до 19,2 месяцев соответственно (р=0,00001). Новый режим показал высокую эффективность и удовлетворительную переносимость и может быть рекомендован для использования в первую линию лечения на базе специализированных центров по лечению сарком на территории РФ.
Об авторе
А. А. Феденко
ФГБУ «Российский онкологический научный центр им. Н.Н. Блохина» МЗ РФ
Россия
Россия
г. Москва
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Рецензия
Для цитирования:
Феденко А.А. Модификация режимов химиотерапии сарком мягких тканей. Старые препараты и новые возможности. Саркомы костей, мягких тканей и опухоли кожи. 2015;(4):3-19.
For citation:
Fedenko A.A. Modifying soft tissue sarcoma chemotherapy regimens. Old drugs and new horizons. Bone and soft tissue sarcomas, tumors of the skin. 2015;(4):3-19. (In Russ.)
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