Application of hyperbaric oxygenation in the treatment of complications after reconstructive surgery in oncology
Abstract
It is known that malignancies lead to the development of tissue hypoxia, or directly related to the acute or chronic hypoxia, which significantly affects the process of tumor growth and metastasis. Since oxygen is necessary for all the major processes involved in wound healing, including resistance to infection, activation of fibroblasts, collagen deposition, angiogenesis and epithelialization, suggested that hyperbaric oxygen therapy (HBOT) promotes the growth of malignant tumors. Thus, for many decades, the focus of researchers was intended to ascertain the validity of this assumption. In the early 2000s Feldmeier, Daruwalla et al. Conducted a literature review about the use of HBOT in oncology. Both authors found that HBO does not promote tumor growth and HBO in patients with malignant tumors is safe. In this article the question of the use of hyperbaric oxygen therapy in treatment of cancer patients, the study of the history of this problem. As well as the results of his own research: the use of HBOT for the treatment of complications after reconstructive operations in oncology.
About the Authors
V. U. Ivashkov
N.N. Blokhin Russian Cancer Research Center Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Moscow
S. V. Sopromadze
N.N. Blokhin Russian Cancer Research Center Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Moscow
R. M. Dokolin
N.N. Blokhin Russian Cancer Research Center Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Moscow
Ju. V. Alimov
N.N. Blokhin Russian Cancer Research Center Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Moscow
V. A. Sobolevsky
N.N. Blokhin Russian Cancer Research Center Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Moscow
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Review
For citations:
Ivashkov V.U., Sopromadze S.V., Dokolin R.M., Alimov J.V., Sobolevsky V.A. Application of hyperbaric oxygenation in the treatment of complications after reconstructive surgery in oncology. Bone and soft tissue sarcomas, tumors of the skin. 2017;(1):46-51. (In Russ.)
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