Preview

Bone and soft tissue sarcomas, tumors of the skin

Advanced search

A case of evaluation of the effectiveness of neoadjuvant radiotherapy in patient with pecoma of pararectal area

Abstract

PEComa is a mesenchymal malignant tumor, which optimal treatment strategy remains undeveloped because of the rarity of occurrence of this tumor. The main treatment is surgery, but investigators continue to search for solutions that could enhance the effectiveness of resection and improve long-term results. This paper presents the case of the relative effectiveness of preoperative hormonal and radiation therapy patient with pelvic PEComa: fixed degree of therapeutic effect in remote tumor was higher than that in the above large meta analysis.

About the Authors

A. V. Nazarenko
N.N. Blokhin Russian Cancer Research Center Ministry of Health of the Russian Federation
Russian Federation

Moscow



E. R. Musaev
N.N. Blokhin Russian Cancer Research Center Ministry of Health of the Russian Federation
Russian Federation

Moscow



S. V. Medvedev
The Moscow P.A. Gertsen Research Institute of Oncology
Russian Federation

Moscow



O. A. Zaspa
N.N. Blokhin Russian Cancer Research Center Ministry of Health of the Russian Federation
Russian Federation

Moscow

 



D. S. Romanov
N.N. Blokhin Russian Cancer Research Center Ministry of Health of the Russian Federation
Russian Federation

Moscow



D. I. Sofronov
N.N. Blokhin Russian Cancer Research Center Ministry of Health of the Russian Federation
Russian Federation

Moscow



V. A. Boldyreva
N.N. Blokhin Russian Cancer Research Center Ministry of Health of the Russian Federation
Russian Federation

Moscow



References

1. Fadare O., Parkash V., Yilmaz Y., Mariappan M.R., Ma L., Hileeto D., Qumsiyeh M.B., Hui P. Perivascular epithelioid cell tumor (PEComa) of the uterine cervix associated with intraabdominal «PEComatosis»: A clinicopathological study with comparative genomic hybridization analysis. World J. Surg. Oncol. 2004, v. 2, p. 35.

2. Cuevas HerrerosO.,EscobarLezcano L., RodriguezBlaco M., Artigas Raventos V. PEComa, a Rare Epithelioid Cell Tumor. Cir. Esp. 2015, v. 93, p. 65-67.

3. Folpe A.L., Mentzel T., Lehr H.A., Fisher C., Balzer B.L., Weiss S.W. Perivascular epithelioid cell neoplasms ofsoft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature. Am. J. Surg. Pathol. 2005, v. 29, p. 1558-1575.

4. Hussain T., Al-Hamali S. Pathophysiology and management aspects of adrenal angiomyolipomas.Ann. R. Coll. Surg.Engl. 2012, v. 94, p. 224-226.

5. Нечушкина И.В., Карселадзе А.И. Пекомы. Обзор литературы и клиническое наблюдение. Саркомы костей, мягких тканей и опухоли кожи. 2016, № 2, с. 32-43.

6. Jonathan S. Bleeker, J. Fernando Quevedo, Andrew L. Folpe. «Malignant» Perivascular Epithelioid Cell Neoplasm: Risk Stratification and Treatment Strategies. Sarcoma. 2012, v. 2012, Article ID 541626, 12 pages. http://dx.doi.org/10.1155/2012/541626.

7. Jeon I.S., Sung M.L. Multimodal treatment using surgery, radiotherapy, and chemotherapy in a patient with a perivascular epithelioid cell tumor of the uterus. Journal of Pediatric Hematology/Oncology. 2005, v. 27, No. 12, p. 681-684.

8. Jeon I.S., Yi D.Y. Acute lymphoblastic leukemia secondary to chemoradiotherapy for perivascular epithelioid cell tumor of uterus. Pediatric hematology and oncology. 2009, v. 26, No. 2, p. 85-88.

9. Osei D.A., Alvandi F., Brooks J.S., Ogilvie C.M. PEComa of the upper extremity: a unique case and description of an initialresponse to neoadjuvant chemotherapy. Sarcoma. 2007, v. 2007, Article ID 53056.

10. Ong L.Y., Hwang W.S., Wong A., Chan M.Y., Chui C.H. Perivascular epithelioid cell tumour of the vagina in an 8 year old girl. Journal ofPediatric Surgery. 2007, v. 42, No. 3, p. 564-566.

11. Weinreb I., Howarth D., Latta E., Ghazarian D., Chetty R. Perivascular epithelioid cell neoplasms (PEComas): four malignant cases expanding the histopathological spectrum and a description of a unique finding. Virchows Archiv. 2007, v. 450, No. 4, p. 463-470.

12. Yamashita K., Fletcher C.D.M. PEComa presenting in bone: clinicopathologic analysis of 6 cases and literature review. American Journal of Surgical Pathology. 2010, v. 34, No. 11, p. 1622-1629.


Review

For citations:


Nazarenko A.V., Musaev E.R., Medvedev S.V., Zaspa O.A., Romanov D.S., Sofronov D.I., Boldyreva V.A. A case of evaluation of the effectiveness of neoadjuvant radiotherapy in patient with pecoma of pararectal area. Bone and soft tissue sarcomas, tumors of the skin. 2017;(1):42-45. (In Russ.)

Views: 98


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2219-4614 (Print)
ISSN 2782-3687 (Online)