Intraoperative radiation therapy in combined treatment of soft tissue sarcomas
A. A. Kurilchik,
A. L. Zubarev,
A. L. Starodubtsev,
V. E. Ivanov,
Yu. V. Gumenetskaya,
A. A. Zheravin,
G. S. Zhamgaryan
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Abstract
Soft tissue sarcomas (STS) are an uncommon group of malignancies, notorious for a high propensity for recurrence and early, mainly hematogenous, metastasizing. Nowadays, combined modality therapy involving radical organ preservation surgery in conjunction with various chemoradiotherapy regimens is the treatment method of choice for STS. In order to improve the efficacy of organ preservation treatment, it is necessary to intensify local treatment of risk areas. Intraoperative radiation therapy (IORT) is one of the methods for intensifying local treatment. In our study, advantages and prospects of development of this approach to combination and concurrent treatment of STS are considered.
About the Authors
A. A. Kurilchik
A.F. Tsyb Medical Radiological Research Center – branch of the Federal State Budget Institution «National Medical Radiological Research Center» of the Health Ministry of the Russian Federation
Russian Federation
Russian Federation
Obninsk
A. L. Zubarev
A.F. Tsyb Medical Radiological Research Center – branch of the Federal State Budget Institution «National Medical Radiological Research Center» of the Health Ministry of the Russian Federation
Russian Federation
Russian Federation
Obninsk
A. L. Starodubtsev
A.F. Tsyb Medical Radiological Research Center – branch of the Federal State Budget Institution «National Medical Radiological Research Center» of the Health Ministry of the Russian Federation
Russian Federation
Russian Federation
Obninsk
V. E. Ivanov
A.F. Tsyb Medical Radiological Research Center – branch of the Federal State Budget Institution «National Medical Radiological Research Center» of the Health Ministry of the Russian Federation
Russian Federation
Russian Federation
Obninsk
Yu. V. Gumenetskaya
A.F. Tsyb Medical Radiological Research Center – branch of the Federal State Budget Institution «National Medical Radiological Research Center» of the Health Ministry of the Russian Federation
Russian Federation
Russian Federation
Obninsk
A. A. Zheravin
A.F. Tsyb Medical Radiological Research Center – branch of the Federal State Budget Institution «National Medical Radiological Research Center» of the Health Ministry of the Russian Federation
Russian Federation
Russian Federation
Obninsk
G. S. Zhamgaryan
A.F. Tsyb Medical Radiological Research Center – branch of the Federal State Budget Institution «National Medical Radiological Research Center» of the Health Ministry of the Russian Federation
Russian Federation
Russian Federation
Obninsk
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Review
For citations:
Kurilchik A.A., Zubarev A.L., Starodubtsev A.L., Ivanov V.E., Gumenetskaya Yu.V., Zheravin A.A., Zhamgaryan G.S. Intraoperative radiation therapy in combined treatment of soft tissue sarcomas. Bone and soft tissue sarcomas, tumors of the skin. 2017;(2):39-45. (In Russ.)
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ISSN 2782-3687 (Online)
ISSN 2782-3687 (Online)
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