Intraoperative radiation therapy in combined treatment of soft tissue sarcomas

A. A. Kurilchik; A. L. Zubarev; A. L. Starodubtsev; V. E. Ivanov; Yu. V. Gumenetskaya; A. A. Zheravin; G. S. Zhamgaryan

Intraoperative radiation therapy in combined treatment of soft tissue sarcomas

A. A. Kurilchik, A. L. Zubarev, A. L. Starodubtsev, V. E. Ivanov, Yu. V. Gumenetskaya, A. A. Zheravin, G. S. Zhamgaryan

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Abstract

Soft tissue sarcomas (STS) are an uncommon group of malignancies, notorious for a high propensity for recurrence and early, mainly hematogenous, metastasizing. Nowadays, combined modality therapy involving radical organ preservation surgery in conjunction with various chemoradiotherapy regimens is the treatment method of choice for STS. In order to improve the efficacy of organ preservation treatment, it is necessary to intensify local treatment of risk areas. Intraoperative radiation therapy (IORT) is one of the methods for intensifying local treatment. In our study, advantages and prospects of development of this approach to combination and concurrent treatment of STS are considered.

Keywords

soft tissue sarcomas, chemoradiotherapy, external beam gamma therapy, intraoperative radiation therapy (IORT), local control, course dose

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For citations:

Kurilchik A.A., Zubarev A.L., Starodubtsev A.L., Ivanov V.E., Gumenetskaya Yu.V., Zheravin A.A., Zhamgaryan G.S. Intraoperative radiation therapy in combined treatment of soft tissue sarcomas. Bone and soft tissue sarcomas, tumors of the skin. 2017;(2):39-45. (In Russ.)

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ISSN 2219-4614 (Print)
ISSN 2782-3687 (Online)

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Bone and soft tissue sarcomas, tumors of the skin

Intraoperative radiation therapy in combined treatment of soft tissue sarcomas

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Abstract

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About the Authors

References

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Bone and soft tissue sarcomas, tumors of the skin

Intraoperative radiation therapy in combined treatment of soft tissue sarcomas

Full Text:

Abstract

Keywords

About the Authors

References

Review

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