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The possibility of surgical treatment of metastatic mesenchymal chondrosarcoma of the lung. Case report

Abstract

Mesenchymal chondrosarcoma is a malignant tumor, characterized by the presence of differentiated cartilage and simultaneously highly vascularized spindle cells or mesenchymal tissue from round shape cells. The case report of 27-year-old patient with a mesenchymal chondrosarcoma of the right temporal bone G3 is presented. In this patient the progression of the disease was discovered 6 years after the manifestation with a metastasis in the right lung. Conducted chemotherapy was ineffective and as a result surgical treatment was performed in the volume of right pneumonectomy with circular resection of the tracheal bifurcation.

About the Authors

B. B. Akhmedov
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia
Russian Federation


M. M. Davydov
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia
Russian Federation


M. A. Ibraev
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia
Russian Federation


I. A. Dadyev
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia; A.I. Evdokimov Moscow State MedicalStomatological University
Russian Federation


References

1. Lightenstein L., Bernstein D. Unusual benign and malignant chondroid tumors of bone. Asurvey of some mesenchymal cartilage tumors and malignant chondroblastic tumors, including a few multicentric ones, as well as many atypical benign chondroblastomas and chondromyxoid fibromas. Cancer [Journal Article]. 1959, v. 12, p. 1142-1157.

2. Shakked R.J., Geller D.S., Gorlick R., Dorfman H.D. Mesenchymal chondrosarcoma: clinicopathologic study of 20 cases. Arch. Pathol. Lab. Med. [Case Reports; Journal Article]. 2012, v. 136 (1), p. 61-75.

3. Cesari M., Bertoni F., Bacchini P., Mercuri M., Palmerini E., Ferrari S. Mesenchymal chondrosarcoma. An analysis of patients treated at a single institution. Tumori [Clinical Trial; Journal Article]. 2007, v. 93 (5), p. 423-427.

4. Nussbeck W., Neureiter D., Soder S., Inwards C., Aigner T. Mesenchymal chondrosarcoma: an immunohistochemical study of 10 cases examining prognostic significance of proliferative activity and cellular differentiation. Pathology [Journal Article; Research Support, NonU.S. Gov’t]. 2004, v. 36 (3), p. 230-233.

5. Louvet C., de Gramont A., Krulik M., Jagueux M., Hubert D., Brissaud P., Sirinelli A., Augereau B., Tubiana J.M., Debray J. Extraskeletal mesenchymal chondrosarcoma: case report and review of the literature. J. Clin. Oncol. [Case Reports; Journal Article]. 1985, v. 3 (6), p. 858-863.

6. Nakashima Y., Unni K.K., Shives T.C., Swee R.G., Dahlin D.C. Mesenchymal chondrosarcoma of bone and soft tissue. A review of 111 cases. Cancer [Journal Article]. 1986, v. 57 (12), p. 2444-2453.

7. Huvos A.G., Rosen G., Dabska M., Marcove R.C. Mesenchymal chondrosarcoma. A clinicopathologic analysis of 35 patients with emphasis on treatment. Cancer [Comparative Study; Journal Article]. 1983, v. 51 (7), p. 1230-1237.

8. Salvati M., Caroli E., Frati A., Piccirilli M., Agrillo A., Brogna C., Occhiogrosso G., Giangaspero F. Central nervous system mesenchymal chondrosarcoma. J. Exp. Clin. Cancer Res. [Case Reports; Journal Article]. 2005, v. 24 (2), p. 317-324.

9. Bloch O.G., Jian B.J., Yang I., Han S.J., Aranda D., Ahn B.J., Parsa A.T. A systematic review of intracranial chondrosarcoma and survival. J. Clin. Neurosci. [Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov’t; Review]. 2009, v. 16 (12), p. 1547-1551.

10. Kawaguchi S., Weiss I., Lin P.P., Huh W.W., Lewis V.O. Radiation therapy is associated with fewer recurrences in mesenchymal chondrosarcoma. Clin. Orthop. Relat. Res. [Journal Article]. 2014, v. 472 (3), p. 856-864.

11. Salvador A.H., Beabout J.W., Dahlin D.C. Mesenchymal chondrosarcoma – observations on 30 new cases. Cancer [Journal Article]. 1971, v. 28 (3), p. 605-615.

12. Dantonello T.M., Int-Veen C., Leuschner I., Schuck A., Furtwaengler R., Claviez A., Schneider D.T., Klingebiel T., Bielack S.S., Koscielniak E. Mesenchymal chondrosarcoma of soft tissues and bone in children, adolescents, and young adults: experiences of the CWS and COSS study groups. Cancer [Journal Article; Multicenter Study; Research Support, Non-U.S. Gov’t]. 2008, v. 112 (11), p. 2424-2431.

13. Hashimoto N., Ueda T., Joyama S., Araki N., Beppu Y., Tatezaki S., Matsumoto S., Nakanishi K., Tomita Y., Yoshikawa H. Extraskeletal mesenchymal chondrosarcoma: an imaging review of ten new patients. Skeletal. Radiol. [Journal Article; Multicenter Study]. 2005, v. 34 (12), p. 785-792.

14. Jie Xu, Dasen Li, Lu Xie, Shun Tang, Wei Guo. Mesenchymal Chondrosarcoma of Bone and Soft Tissue: A Systematic Review of 107 Patients in the Past 20 Years. U.S. National Library of Medicine. 2015.

15. Frezza A.M. et al. Mesenchymal chondrosarcoma: prognostic factors and outcome in 113 patients. A European Musculoskeletal Oncology Society study. Eur. J. Cancer. 2015, v. 51 (3), p. 374-381.

16. Практические рекомендации по лечению злокачественных опухолей Российского общества клинической онкологии 2017 г.

17. Lee S.Y., Lim Y.C., Song M.H., Seok J.Y., Lee W.S., Choi E.C. Chondrosarcoma of the head and neck. Yonsei Med. J. 2005, v. 46 (2), p. 228-232. DOI: 10.3349/ymj.2005.46.2.228.7


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For citations:


Akhmedov B.B., Davydov M.M., Ibraev M.A., Dadyev I.A. The possibility of surgical treatment of metastatic mesenchymal chondrosarcoma of the lung. Case report. Bone and soft tissue sarcomas, tumors of the skin. 2017;(4):43-45. (In Russ.)

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ISSN 2219-4614 (Print)
ISSN 2782-3687 (Online)