Синхронное развитие локального рецидива и отдаленных метастазов у пациентов с саркомами мягких тканей

Рецидивирование и метастазирование делают проблему лечения больных с саркомами мягких тканей опорно-двигательного аппарата чрезвычайно трудной. Появление отдаленных метастазов достоверно значительно уменьшает общую выживаемость. По данным большинства исследователей, так же влияет на выживаемость развитие локального рецидива. Особый интерес представляет группа пациентов с синхронным развитием локального и отдаленного поражения. В отделе общей онкологии РОНЦ им. Н.Н. Блохина РАМН в 2003-2008 годах находились на лечении 27 больных с сочетанным одномоментным появлением рецидивного и метастатического процесса. Среднее время от момента появления первичной опухоли до развития синхронного поражения - 11,1 мес. Общая 3 -летняя выживаемость данной группы пациентов - 42%. Продолжаются клинические разработки стадирующей системы для пациентов с локальным рецидивом сарком мягких тканей для формирования подгрупп больных с разными показателями выживаемости и рационального лечения на основе их прогноза.

саркома мягких тканей, рецидив, метастаз

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