MALIGNANT FIBROUS HISTIOCYTOMA. THE RESULTS OF COMBINED TREATMENT OF RESECTABLE FORMS
Abstract
Background. We studied the patients' outcome with respectable forms of malignant fibrous histiocytoma according to the
type of chemotherapy. Methods. We performed a retrospective analysis of 53 patients with malignant fibrous histiocytoma treated in the N.N. Blokhins
Russian Cancer Research Center from 2000 to 2010. All patients underwent radical surgery. Neoadjuvant chemotherapy
was administered in 7 (13%) patients, adjuvant chemotherapy - in 5 (9%), neo and adjuvant chemotherapy - in 13 (24%)
patients, chemotherapy was not done in 28 (54%) patients. Result. Progression of the disease was revealed in 6/7 (86%), 7/18 (39%), 17/28 (60%) respectively. Conclusion. Patients with MFH should be prescribed adjuvant chemotherapy for reducing the risk of relapse.
type of chemotherapy. Methods. We performed a retrospective analysis of 53 patients with malignant fibrous histiocytoma treated in the N.N. Blokhins
Russian Cancer Research Center from 2000 to 2010. All patients underwent radical surgery. Neoadjuvant chemotherapy
was administered in 7 (13%) patients, adjuvant chemotherapy - in 5 (9%), neo and adjuvant chemotherapy - in 13 (24%)
patients, chemotherapy was not done in 28 (54%) patients. Result. Progression of the disease was revealed in 6/7 (86%), 7/18 (39%), 17/28 (60%) respectively. Conclusion. Patients with MFH should be prescribed adjuvant chemotherapy for reducing the risk of relapse.
About the Authors
О. Сехина
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
М. Федянин
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
Е. Яковлева
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
А. Буланов
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
Б. Бохян
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
O. V. Sekhina
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
M. U. Fedyanin
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
E. S. Yakovleva
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
A. A. Bulanov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
B. Y. Bokhyan
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
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Review
For citations:
, , , , , Sekhina O.V., Fedyanin M.U., Yakovleva E.S., Bulanov A.A., Bokhyan B.Y. MALIGNANT FIBROUS HISTIOCYTOMA. THE RESULTS OF COMBINED TREATMENT OF RESECTABLE FORMS. Bone and soft tissue sarcomas, tumors of the skin. 2011;(4):37-40. (In Russ.)
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