EUS scanning in differential diagnostics of various macroscopic forms of non-Hodgkin’s lymphomas and non-epitelial gastric tumors

Abstract

Nowadays diagnostics of gastric malignant lymphomas is still a big challenge due to wide polymorphism of visual picture and is frequently misdiagnosed with cancer or non-epithelial gastric tumors. Aim of the study. To improve ultrasonic diagnostics of gastric non-Hodgkins lymphomas by novel differential and diagnostic criteria. Materials and methods. 250 patients with gastric non-Hodgkins lymphomas and 40 patients with macroscopic non-epithelial gastric tumors were evaluated. All patients underwent esophagogastroscopy following EUS scanning and tumor biopsy. Results. EUS scanning during ambulatory primary patient evaluation may exclude epithelial tumors from differential diagnosis and suppose its histologic structure according to underlying tumor gastric wall layer, presence of capsule, contours characters, echostructure homogeneity and regional lymphoid collectors condition. After detailed evaluation of these parameters final impression can be made and biopsy method maybe chosen. EUS picture of various non-epitelial tumors had specific signs which allowed to carry out differential diagnostics from gastric non-Hodgkin lymphomas during scanning.