Soft tissue sarcoma in children and adolences in Russia: population study
Abstract
The aim of this study was to investigate the soft tissue sarcoma (STS) in children and adolescents in Russia. We consider both temporal and geographical variations. The Annual reports of Ministry of health and Federal State Statistics Service were used to extract information on cases (1989-2011) and deaths (1999-2011) including gender, age and geographic information. Population data were also obtained and analyses included descriptive summaries, rates, and trend detection tests. The age-adjusted incidence rate of STS in children aged 0-17 years was 7,2 per 1 000 000 individuals per year for 2007 to 2011 (931 incident cases). The highest age-specific incidence 11,3 per 1 000 000 children/year was observed in early childhood (0-4 years). There were more than doubling of average Russian incidence rates in some areas. Between 1989 and 2011, a significant increase in the incidence of STS in children aged 0-14 years was observed (AAPC=3,9% [95%CI, 3,3%-4,4%] with the greatest increase in children aged 0-4 years (AAPC=5,4% [95% CI, 4,76,3]. This trend may have been attributable mainly to advances in diagnostics. Mortality from childhood STS was very high for this period (531 deaths, 4,2 per 1 000 000 children/year) and the greatest death rate (6,9 per 1 000 000 children/year) was observed in children aged 1-4 years. Conclusions: significant temporal and geographical variations of childhood STS were found during the study period. Further study is required to explain higher rate areas.
About the Authors
T. H. Men
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
M. D. Aliyev
FGBU N.N. Blokhin Russian Cancer Research Center
Russian Federation
Russian Federation
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Review
For citations:
Men T.H., Aliyev M.D. Soft tissue sarcoma in children and adolences in Russia: population study. Bone and soft tissue sarcomas, tumors of the skin. 2013;(1):3-10. (In Russ.)
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