Local antibacterial prophylaxis in oncoorthopedics
Abstract
Forty surgical resections with intraoperative use of collagen sponges (Collatamp® EG) impregnated with antibiotic (gentamicin) were performed. The average age of patients was 45 (from 18 to 65). There were no infection complications in the early postoperative period. Collatamp EG can be recommended for orthopaedical patients with high risk of wound infection as additional agent for local antibiotic prophylaxis.
About the Authors
V. V. Teplyakov
P.A. Gertzen Moscow Cancer Research Center
Russian Federation
Russian Federation
Moscow
A. V. Bukcharov
P.A. Gertzen Moscow Cancer Research Center
Russian Federation
Russian Federation
Moscow
V. A. Derzhavin
P.A. Gertzen Moscow Cancer Research Center
Russian Federation
Russian Federation
Moscow
References
1. Parvizi J., Azzam K., Ghanem E., Austin M.S., Rothman R.H. Periprosthetic Infection Due to Resistant Staphylococci. Clin. Orthop. Relat. Res. 2009, p. 467.
2. Phillips J.E., Crane T.P., Noy M., Elliott T.S., Grimer R.J. The incidence of deep prosthetic infections in a specialist orthopaedic hospital: a 15-year prospective survey. J. Bone Joint Surg. Br 2006, v. 88, p. 943-948.
3. Cavanaugh D., Berry J., Yarboro S. et al. Better Prophylaxis Against Surgical Site Infection with Local as Well as Systemic Antibiotics. J. of Bone and Joint Surgery Am. 2009, p. 1907-1911.
4. Trampuz A., Widmer A.F. Infections associated with orthopaedic implants. Curr. Opin. Infect. Dis. 2006, v. 19, p. 349-356.
5. Engesaeter L.B., Lie S.A., Espehaug B. et al. Antibiotic prophylaxis in total hip arthroplasty: effects of antibiotic prophylaxis systemically and in bone cement on the revision rate of 22,170 primary hip replacements followed 0-14 years in the Norwegian Arthroplasty Register. Acta Orthop. Scand. 2003, v. 74 (6), p. 644-651.
6. Pulido L., Ghanem E., Joshi A., Purtill J.J., Parvizi J. Periprosthetic Joint Infection. Clin. Orthop. Relat. Res. 2008, v. 466, p. 1710-1715.
7. Neut D., van de Belt H., van Horn J.R. et al. Residual gentamicin-release from antibiotic-loaded polymethylmathacrylate beads after 5 years of implantation. Biomaterials. 2003, v. 24 (10), p. 1829-1831.
8. Mendel V., Simanowski H., Scholz H. et al. Therapy with gentamicin-PMMA beads, gentamicin-collagen sponge, and cefazolin for experimental osteomyelitis due to Staphylococcus aureus in rats. Arch. Orthop. Trauma Surg. 2005, v. 125 (6), p. 363-368.
Review
For citations:
Teplyakov V.V., Bukcharov A.V., Derzhavin V.A. Local antibacterial prophylaxis in oncoorthopedics. Bone and soft tissue sarcomas, tumors of the skin. 2014;(1):49-52. (In Russ.)
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