Surgical treatment of retroperitoneal tumors involving vena cava inferior
Abstract
Aim. Improve the results of surgical treatment of retroperitoneal tumors involving vena cava inferior.
Materials and methods. 18 patients with retroperitoneal tumors underwent vena cava inferior resection at the p.a. Herzen oncology institution from 2010 to 2016. Nine patients had leiomyosarcoma, 4 – liposarcoma, 2 – intraabdominal desmoid tumor and neuroblastoma, 1 – gastrointestinal stromal tumor. in all cases we observed involving vena cava inferior upper or below of renal vessels in tumor process.
Results. All patients had R0 surgical margin in vena cava wall. 8 patients were performed marginal resection vena cava and 8 – segmental. 3 patients underwent vena cava prosthesis and five patients were without reconstruction, it was determined good venous collateral system. Early complications developed in 4 patients and one of them died. the mean follow-up was 14 months (from 6 to 76). Three patients died from the disease progression and others are alive without signs of disease.
Conclusion. Involving vena cava inferior in tumor process is not a contraindication for surgical treatment. Complication rate is not high. The use of modern methods of reconstructive surgery allows to extend indication for surgical treatment retroperitoneal tumors.
About the Authors
A. D. KaprinRussian Federation
Moscow
A. B. Riabov
Russian Federation
Moscow
V. M. Chomiakov
Russian Federation
Moscow
V. V. Cheremisov
Russian Federation
Moscow
V. E. Horonenko
Russian Federation
Moscow
V. I. Chissov
Russian Federation
Moscow
N. N. Volchenko
Russian Federation
Moscow
I. V. Kolobaev
Russian Federation
Moscow
A. V. Chaika
Russian Federation
Moscow
D. O. Trunov
Russian Federation
Moscow
A. V. Ivanov
Russian Federation
Moscow
A. K. Kostrigin
Russian Federation
Moscow
D. M. Pugaev
Russian Federation
Moscow
A. M. Stecuk
Russian Federation
Moscow
References
1. Singer S., Maki R.G., O’Sullivan B. Soft tissue sarcoma. In: DeVita V.T. Jr, Lawrence T.S., Rosenberg S.A. Cancer: principles and practice of oncology. 9th ed. Philadelphia: Lippincott Williams & Wilkins. 2011, p. 1533-1577.
2. Стилиди И.С., Губина Г.И., Неред С.Н., Клименков А.А., Сельчук В.И. Непосредственные результаты хирургического лечения неорганных забрюшинных опухолей. Вестн. Московского онкологич. общества. 2006, № 5.
3. Erzen D., Sencar M., Novak J. Retroperitoneal sarcoma: 25 years of experience with aggressive surgical treatment at the Institute of Oncology, Ljubljana. J. Surg. Oncol. 2005, v. 91 (1), p. 1-9. DOI: 10.1002/jso.20265.
4. Вашакмадзе Л.А., Черемисов В.В., БутенкоА.В. Онкология: национальное руководство под ред. Чиссова В.И., Давыдова М.И. ГЭОТАР-Медиа. 2008, с. 739-748.
5. Gronchi A., Casali P.G., Fiore M. et al. Retroperitoneal soft tissue sarcomas: patterns of recurrence in 167 patients treated at a single institution. Cancer. 2004, v. 100, p. 2448-2455. DOI: 10.1002/cncr.20269.
6. Lehnert T., Cardona S., Hinz U. et al. Primary and locally recurrent etroperitoneal soft-tissue sarcoma: local control andsurvival. Eur. J. Surg. Oncol. 2009, v. 35, p. 986-993. DOI: 10.1007/s00423-012-0941-9.
7. Чиссов В.И., Вашакмадзе Л.А., Бутенко А.А., Черемисов В.В., Хомяков В.М. Современные подходы и факторы прогноза при первичных и рецидивных неорганных опухолях забрюшинного пространства. Рос. онкологич. журн. 2011, № 3, с. 4-10.
8. Anaya D.A., Lahat G., Liu J. et al. Multifocality in retroperitoneal sarcoma: a prognostic factor critical to surgical decision-making. Ann. Surg. 2009, v. 249, p. 137-142. DOI: 10.1097/SLA.0b013e3181928f2f.
9. Каприн А.Д., Рябов А.Б., Черемисов В.В., Хомяков В.М., Новикова О.В., Кострыгин А.К., Стецюк А.Н. Десмоидная фиброма забрюшинного пространства с вовлечением нижней полой вены и мочеточника. Онкология. Журнал им. П.А. Герцена. 2016, № 3, с. 65-70.
10. Чиссов В.И., Вашакмадзе Л.А., Бутенко А.А., Черемисов В.В., Хомяков В.М. Современные подходы и факто- ры прогноза при первичных и рецидивных неорганных опухолях забрюшинного пространства. Российский онкологический журнал. 2011, № 3, с. 4-10.
11. Jean Hardwigsen, MD, Patrick Baqué, MD, Bernard Crespy, MD, Vincent Moutardier, MD, Jean Robert Delpero, MD, Yves Patrice Le Treut, MD. An of surgery. Vol. 233, No. 2, p. 242-249. Resection of the Inferior Vena Cava for Neoplasms With or Without Prosthetic Replacement: A 14-Patient Series. PMCID: PMC1421207.
12. Mingoli A., Cavallaro A., Sapienza P. et al. International reg- istryof inferior vena cava leiomyosarcoma: analysis of a world series on 218 patients. Anticancer Res. 1996, v. 16, p. 3201-3205. DOI: http://dx.doi.org/10.1016/j.jvs.2009.07.111. 13. Wachtel H., Gupta M., Jackson B.M., Kelz R.R., Karakou- sis G.C., Fraker D.L., Roses R.E. Outcomes after resection
13. of the inferior vena cava: a pooled data analysis of 377 cases. Surg. Oncol. 2015, v. 24 (1), p. 21-27. DOI: 10.4103/0971-5851.180134.
14. Виноградов А.Л., Вашакмадзе Л.А., Никитаев Н.С. Хирургическая тактика при опухолях забрюшинного пространства, связанных с нижней полой веной. Советская медицина. 1987, № 8.
15. William Quinones-Baldrich, Ali Alktaifi, Fritz Eilber, Frederick Eilber. Inferior vena cava resection and reconstruction for retroperitoneal tumor excision. Presented at the Twenty-sixth Annual Meeting of the Western Vascular Society, Kauai, Hawaii, September 17-20, 2011. J. Vasc. Surg. May 2012, v. 55, Issue 5, p. 1386-1393. DOI: http://dx.doi.org/10.1016/j.jvs.2011.11.054.
16. Illuminati G., CalioF., D’UrsoA. et al. Prosthetic replacement of the infrahepatic inferior vena cava for leiomyosarcoma. Arch. Surg. 2006, v. 141, p. 919-924. DOI: 10.1001/archsurg.141.9.919.
17. Hicks C.W., Glebova N.O., Piazza K.M., Orion K., Pierorazio P.M., Lum Y.W., Abularrage C.J., Black J.H. 3rd. Risk of venous thromboembolic events following inferior vena cava resection and reconstruction. J. Vasc. Surg. 2016, v. 63 (4), p. 1004-1010.
Review
For citations:
Kaprin A.D., Riabov A.B., Chomiakov V.M., Cheremisov V.V., Horonenko V.E., Chissov V.I., Volchenko N.N., Kolobaev I.V., Chaika A.V., Trunov D.O., Ivanov A.V., Kostrigin A.K., Pugaev D.M., Stecuk A.M. Surgical treatment of retroperitoneal tumors involving vena cava inferior. Bone and soft tissue sarcomas, tumors of the skin. 2016;(3):48-59. (In Russ.)