Low-grade central osteosarcoma. Review
Abstract
Low-grade central osteosarcoma is a rare subtype of intramedullary osteosarcoma (approximately 1% of all osteosarcomas) that characterized histologically by a spindle cell proliferation associated with trabecular bone formation, and is usually located in the long bones with a predilection for the distal femur and proximal tibia. It has the potential to recur, dedifferentiate, and metastasize subsequent to surgical treatment. Sometimes it is difficult to make a diagnosis and differentiate it with fibrous dysplasia and desmoplastic fibroma. In such cases, careful radiological interpretation is helpful. This tumor usually carries a good prognosis.
About the Authors
D. V. Rogozhin
Russian Children’s Clinical Hospital;
Research Center of Pediatric Hematology, Oncology and Immunology
Russian Federation
Russian Federation
Moscow
D. M. Konovalov
Russian Children’s Clinical Hospital;
Research Center of Pediatric Hematology, Oncology and Immunology
Russian Federation
Russian Federation
Moscow
A. G. Talalaev
Russian Children’s Clinical Hospital;
Research Center of Pediatric Hematology, Oncology and Immunology
Russian Federation
Russian Federation
Moscow
V. Yu. Roschin
Russian Children’s Clinical Hospital;
Research Center of Pediatric Hematology, Oncology and Immunology
Russian Federation
Russian Federation
Moscow
N. A. Bolshakov
Russian Children’s Clinical Hospital;
Research Center of Pediatric Hematology, Oncology and Immunology
Russian Federation
Russian Federation
Moscow
M. V. Tikhonova
Russian Children’s Clinical Hospital;
Research Center of Pediatric Hematology, Oncology and Immunology
Russian Federation
Russian Federation
Moscow
A. N. Remizov
Russian Children’s Clinical Hospital;
Research Center of Pediatric Hematology, Oncology and Immunology
Russian Federation
Russian Federation
Moscow
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Review
For citations:
Rogozhin D.V., Konovalov D.M., Talalaev A.G., Roschin V.Yu., Bolshakov N.A., Tikhonova M.V., Remizov A.N. Low-grade central osteosarcoma. Review. Bone and soft tissue sarcomas, tumors of the skin. 2016;(3):16-21. (In Russ.)
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