Extrarenal rhabdoid tumors in children. Case report
Abstract
The search for neoadjuvant chemotherapy in pediatric patients with rhabdoid tumors is under way. As illustrated by this case report, etoposide/ifosfamide combination could be used as neoadjuvant treatment for patient with rhabdoid tumor.
About the Authors
D. B. Khestanov
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia
Russian Federation
Russian Federation
O. A. Romantsova
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia
Russian Federation
Russian Federation
V. V. Kochneva
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia
Russian Federation
Russian Federation
V. V. Hayrulova
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia
Russian Federation
Russian Federation
E. R. Senzhapova
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia
Russian Federation
Russian Federation
A. Z. Dzampaev
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia
Russian Federation
Russian Federation
A. A. Fedenko
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia
Russian Federation
Russian Federation
M. D. Aliev
FGBU «National Medical Research Center of Oncology named after N.N. Blokhin» of the Ministry of Health of Russia
Russian Federation
Russian Federation
References
1. Ammerlaan AC, Ararou A, Houben MP, Baas F, Tijssen CC, Teepen JL, Wesseling P, Hulsebos TJ. Long-term survival and transmission of INI1-mutation via nonpenetrant males in a family with rhabdoid tumour predisposition syndrome. Br J Cancer. 200829;98(2):474-479. Epub 2007 Dec 18.
2. Athale UH, Duckworth J, Odame I, Barr R. Childhood atypical teratoid rhabdoid tumor of the central nervous system: a meta-analysis of observational studies. J Pediatr Hematol Oncol. 2009;31(9):651-663.
3. Biegel JA, Zhou JY Rorke LB, Stenstrom C, Wainwright LM et al. Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors. Cancer Res. 1999;59:74-79 [PubMed].
4. Bourdeaut F, Fréneaux P, Thuille B, Bergeron C, Laurence V, Brugières L, Vérité C, Michon J, Delattre O, Orbach D. Extra-renal non-cerebral rhabdoid tumours. Pediatr Blood Cancer. 2008;51(3):363-368. DOI: 10.1002/pbc.21632.
5. Brennan BM, Foot AB, Stiller C, Kelsey A, Vujanic G, Grundy R, Pritchard Jones K. Where to next with extracranial rhabdoid tumours in children. United Kingdom Children’s Cancer Study Group (UKCCSG). Eur J Cancer. 2004;40(4):624-626.
6. Chao MF, Su YF, Jaw TS, Chiou SS, Lin CH. Atypical teratoid/rhabdoid tumor of lumbar spine in a toddler child. Spinal Cord Ser Cases. 2017;3:16026. DOI: 10.1038/scsandc. 2016.26.
7. Chiou SH, Kao CL, Chen YW, Chien CS, Hung SC, Lo JF, Chen YJ, Ku HH, Hsu MT, Wong TT Identification of CD133-positive radioresistant cells in atypical teratoid/ rhabdoid tumor. PLoS One. 2008;3(5):e2090. DOI: 10.1371/ journal.pone.0002090.
8. Chi SN, Zimmerman MA, Yao X, Cohen KJ, Burger P, Biegel JA, Rorke-Adams LB, Fisher MJ, Janss A, Mazewski C, Goldman S, Manley PE, Bowers DC, Bendel A, Rubin J, Turner CD, Marcus KJ, Goumnerova L, Ullrich NJ, Kieran MW. Intensive multimodality treatment for children with newly diagnosed CNS atypical teratoid rhabdoid tumor. J Clin Oncol. 2009;27(3):385-389. DOI: 10.1200/JCO.2008.18.7724. Epub 2008 Dec 8.
9. Corey SJ, Andersen JW, Vawter GF, Lack EE, Sallan SE. Improved survival for children with anaplastic Wilms’ tumors. Cancer. 1991;68(5).
10. Eaton KW Tooke LS, Wainwright LM, Judkins AR, Biegel JA. Spectrum of SMARCB1/INI1 mutations in familial and sporadic rhabdoid tumors. Pediatr Blood Cancer. 2011;56(1):7-15. DOI: 10.1002/pbc.22831.
11. Dallorso S, Dini G, Ladenstein R, Cama A, Milanaccio C, Barra S, Cappelli B, Garrè ML; EBMT-PDWP Evolving role of myeloablative chemotherapy in the treatment of childhood brain tumours. Bone Marrow Transplant. 2005;35 Suppl 1:S31-4.
12. Jackson EM, Sievert AJ, Gai X, Hakonarson H, Judkins AR et al. (2009) Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors. Clin Cancer Res. 15:1923-1930 [PMC free article] [PubMed].
13. Kodet R, Newton WA Jr, Sachs N, Hamoudi AB, Raney RB, Asmar L, Gehan EA. Rhabdoid tumors of soft tissues: a clinicopathologic study of 26 cases enrolled on the Intergroup Rhabdomyosarcoma Study. Hum Pathol. 1991;22(7):674-684.
14. Kohashi K, Oda Y, Yamamoto H, Tamiya S, Matono H et al. Reduced expression of SMARCB1/INI1 protein in synovial sarcoma. Mod Pathol. 2010;23:981-990.
15. Madigan CE, Armenian SH, Malogolowkin MH, Mascar-enhas L. Extracranial malignant rhabdoid tumors in childhood: the Childrens Hospital Los Angeles experience. Cancer. 2007;110(9):2061-2066.
16. Reinhard H, Reinert J, Beier R, Furtwängler R, Alkasser M, Rutkowski S, Frühwald M, Koscielniak E, Leuschner I, Kaatsch P, Graf N. Rhabdoid tumors in children: prognostic factors in 70 patients diagnosed in Germany. Oncol Rep. 2008;19(3):819-823.
17. Rousseau-Merck MF, Versteege I, Legrand I, Couturier J, Mairal A et al. hSNF5/INI1 inactivation is mainly associated with homozygous deletions and mitotic recombinations in rhabdoid tumors. Cancer Res. 1999;59:3152-3156 [PubMed].
18. Schneppenheim R, Frühwald MC, Gesk S, Hasselblatt M, Jeibmann A, Kordes U, Kreuz M, Leuschner I, Martin Subero JI, Obser T, Oyen F, Vater I, Siebert R. Germline nonsense mutation and somatic inactivation of SMARCA4/BRG1 in a family with rhabdoid tumor predisposition syndrome. Am J Hum Genet. 2010;86(2):279-284. DOI: 10.1016/j.ajhg.2010.01.013. Epub 2010 Feb 4.
19. Sevenet N, Sheridan E, Amram D, Schneider P, Handgretinger R et al. Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers. Am J Hum Genet. 1999;65:1342-1348 [PMC free article] [PubMed].
20. Trobaugh-Lotrario AD, Tomlinson GE, Finegold MJ, Gore L, Feusner JH. Small cell undifferentiated variant of hepatoblastoma: adverse clinical and molecular features similar to rhabdoid tumors. Pediatr Blood Cancer. 2009;52:328-334.
21. Versteege I, Medjkane S, Rouillard D, Delattre O. A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle. Oncogene. 2002;21:6403-6412 [PubMed].
22. Versteege I, Sevenet N, Lange J, Rousseau-Merck MF, Ambros P et al. Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature. 1998;394:203-206 [PubMed].
Review
For citations:
Khestanov D.B., Romantsova O.A., Kochneva V.V., Hayrulova V.V., Senzhapova E.R., Dzampaev A.Z., Fedenko A.A., Aliev M.D. Extrarenal rhabdoid tumors in children. Case report. Bone and soft tissue sarcomas, tumors of the skin. 2018;10(2):49-54. (In Russ.)
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