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Bone and soft tissue sarcomas, tumors of the skin

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SYNCHRONOUS DEVELOPMENT OF LOCAL RECURRENCE AND DISTANT METASTASES IN PATIENTS WITH SOFT TISSUE SARCOMA

Abstract

Recurrence and metastasis make a big problem the treatment of patients with soft tissue extremely sarcoma. The appearance of distant metastases significantly reduces the overall survival. According to most publications, the same effect on the survival of the development of local recurrence is observed. Of particular interest is the group of patients with synchronous development of local and distant failure. The Department of General Oncology of Russian Cancer Research Center NN Blokhin in 2003-2008 have treated 27 patients with combined one-stage appearance of recurrent and metastatic process. The average time from onset of the primary tumor to the development of synchronous lesions was 11,1 months. The overall 3 year survival rate for this group of patients was 42%. We developed a staging system for patients with local recurrence of soft tissue sarcomas to form subgroups of patients with different rates of survival and rational treatment based on their prognosis.

About the Authors

Д. Мартынков
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation


Т. Харатишвили
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation


Б. Бохян
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation


А. Феденко
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation


Д. Буров
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation


М. Алиев
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation


Н. Петроченко
Российский онкологический научный центр им. Н.Н. Блохина РАМН
Russian Federation


D. V. Martynkov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation


Т. К. Kharatishvili
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation


B. Y. Bohyan
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation


A. A. Fedenko
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation


D. A. Burov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation


M. D. Aliev
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation


N. S. Petrochenko
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation


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 ,  ,  ,  ,  ,  ,  , Martynkov D.V., Kharatishvili Т.К., Bohyan B.Y., Fedenko A.A., Burov D.A., Aliev M.D., Petrochenko N.S. SYNCHRONOUS DEVELOPMENT OF LOCAL RECURRENCE AND DISTANT METASTASES IN PATIENTS WITH SOFT TISSUE SARCOMA. Bone and soft tissue sarcomas, tumors of the skin. 2011;(4):51-55. (In Russ.)

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