Soft tissue sarcomas diagnostic mistakes
Abstract
Malignant soft tissue tumors are very rear and makes less then 1% of all cancers. They are characterized with a rapid aggressive onset, high frequency of local recurrences and high metastatic potential. Even nowadays there are a lot of difficulties during primary diagnostics of this rear group of malignancies that leads to misdiagnosis, wrong treatment algorithms and finally to increased tumor growth. Reasons of late and misdiagnostics are widely discussed in this article.
About the Authors
D. A. Burov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
B. Yu. Bokhyan
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
A. A. Fedenko
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
V. A. Khailenko
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
M. D. Aliev
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
References
1. Бебякин В.Г., Минуплин Ф.Ш. Ошибки в диагностике злокачественных опухолей мягких тканей. Вопр. онкол. Помощи на этапе реформирования здравоохранения. Екатеринбург, 1996, с. 20-21.
2. Блинова Н.Н., Веснина А.Г., Пучкова Ю.Г. Диагностика злокачественных опухолей при диспансеризации населения. СПб.: Гиппократ, 1994, с. 224.
3. Веснин А.Г., Семенов И.И. Атлас лучевой диагностики опухолей опорно-двигательного аппарата: Часть 2: Опухоли мягких тканей. СПб., Невский диалект, 2003.
4. Данилова Т.В. Хирургия новообразований грудной стенки.: Автореф. диссерт. мед. наук, 1992, с. 19.
5. Кочнева В.А. Клиника, дифференциальная диагностика и стадирование сарком мягких тканей. Практическая онкология. 2004, т. 5, № 4, с. 237-242.
6. Лукьянченко А.Б., Симонова Г.Т., Долгушин Б.И. и соат. Комплексная диагностика опухолей мягких тканей туловища и конечностей. Вестн. ВОНЦ АМН. 1998, № 1, с. 56-59.
7. Нуднова Н.В., Кошелева Н.В., Ганова Е.В. МР-томог- рафическая диагностика опухолей мягких тканей. Вес- тн.рентгенологии и радиологии. 1999, № 6, с. 35-38.
8. Трапезников Н.Н., Кныш И.Т, Клименков А.А., Кост- рыба И.М. Злокачественные опухоли мягких тканей конечностей и туловища. Киев, 1981.
9. Тришкин В.А., Веснин А.Г., Столяров В.И. и соат. Сравнительный анализ современных методов амбулаторной диагностики опухолей мягких тканей. Вестник хирургии им. И.И. Грекова. 1994, т. 152, с. 93-98.
10. Тришкин В.А., Столяров В.И. Трудности и ошибки амбулаторной диагностики сарком мягких тканей Ошибки, трудности, осложнений. НИИ онкологии им. Н.Н. Петрова, 1988.
11. Чибисова М.А., Тютин Л.А. МРТ-диагностика заболеваний костно-мышечной системы. Клиническое применение магнитно-резонансной томографии с контрастным усилением. Под ред. Ю.Н. Беленкова, С.К. Тернового, О.И. Беличенко. М., Видар, 1996, с. 50-57.
12. Barroca H. Fine needle biopsy and genetics, two allied weapons in the diagnosis, prognosis, and target therapeutics of solid pediatric tumors. Diagn Cytopathol. 2008, v. 36 (9), p. 678-684.
13. Carrasco C.H. Angiography of osteosarcoma. Hematol Oncol Clin. North Am. 1995.
14. Cheng E.Y., Dusenbery K.E., Winters M.R., Thompson R.C. Soft tissue sarcomas: preoperative versus postoperative radiotherapy. J. Surg. Oncol. 1996, v. 61, p. 90-99.
15. Choi H., Varma D.G., Fornage B.D., Kim E.E. Johnston DA Soft-tissue sarcoma: MR imaging vs sonography for detection of local recurrence after surgery American Journal of Roentgenology. V. 157, p. 353-358.
16. Coindre J.M., Terrier P, Guillou L. et al. Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas: a study of 1240 patients from the French Federation of Cancer Centers Sarcoma Group. Cancer. 2001, v. 91, p. 1914-1926.
17. Cormier J.N., Pollock R.E. Soft tissue sarcomas CA Cancer. J. Clin. 2004, v. 54 (2), p. 94-109.
18. Das D.K. Fine-needle aspiration (FNA) cytology diagnosis of small round cell tumors: value and limitations. Indian J. Pathol. Microbiol. 2004, v. 47 (3), p. 309-318.
19. Davicioni E., Wai D.H., Anderson M.J. Diagnostic and prognostic sarcoma signatures. Mol. Diagn. Ther. 2008, v. 12 (6), p. 359-374.
20. Demetri G.D. Major developments in the understanding and treatment of soft-tissue sarcomas in adults. Curr. Opin Oncol. 1998, v. 10 (4), p. 343-347.
21. Domanski HA.Fine-needle aspiration cytology of soft tissue lesions: diagnostic challenges. Diagn. Cytopathol. 2007, v. 35 (12), p. 768-773.
22. Donohue J.H., Collin C., Friedrich C. et al. Brennan MF. Low-grade soft tissue sarcomas of the extremities. Cancer (Phila). 1988, v. 62, p. 184-193.
23. El-Jabbour J.N., Akhtar S.S., Kerr G.R. et al. Prognostic factors for survival in soft tissue sarcoma. Br. J. Cancer. 1990, v. 34 (6), p. 857-861.
24. Estourgie S.H., Nielsen G.P, Ott M.J. Metastatic patterns of extremity myxoid liposarcoma and their outcome. J. Surg. Oncol. 2002, v. 80 (2), p. 89-93.
25. Fujii J., Ozaki T, Kawai A. et al. Angiography for assessment of preoperative chemotherapy in musculoskeletal sarcomas. Clin. Orthop. Relat. Res. 1999, v. 360, p. 197-206.
26. Gelineck J., Keller J., Jensen O.M. et al.Evaluation of li- pomatous soft tissue tumors by MR Imaging. Acta Radiol. 1994, v. 35, p. 367-370.
27. Gordon B.A., Flanagan F.L., Dehdashti F. Whole-body positron emission tomography: normal variations, pitfalls, and technical considerations. AJR Am. J. Roentgenol. 1997, v. 169, p. 1675-1680.
28. Guillou L., Coindre J.M., Bonichon F. et al. Comparative study of the National Cancer Institute and French Federation of Cancer Centers Sarcoma Group grading systems in a population of 410 adult patients with oft tissue sarcoma. J. Clin. Oncol. 1997, v. 15, p. 350-362.
29. Heslin M.J., Lewis J.J., Nadler E. et al. Prognostic factors associated with long-term survival for retroperitoneal sarcoma: implications for management. J. Clin. Oncol. 1997, v. 15 (8), p. 2832-2829.
30. Jemal A., Siegel R., Ward E. et al. Cancer statistics, 2007. CA Cancer. J. Clin. 2007, v. 57, p. 43-66.
31. Johnson G.R., Zhuang H., Khan J. et al. Role of positron emission tomography with fluorine- 18-deoxyglucose in the detection of local recurrent and distant metastatic sarcoma. Clin. Nucl. Med. 2003, v. 28, p. 815-820.
32. Knapp E.L., Kransdorf M.J., Letson G.D. Diagnostic imaging update: soft tissue sarcomas. Cancer. Control. 2005, v. 12 (1), p. 22-26.
33. Kransdorf M.J., Murphey M.D. Radiologic evaluation of soft tissue masses: a current perspective. A.J.R. 2000, v. 175, No. 3, p. 575-587.
34. Mankin H.J., Lange T.A., Spanier S.S. The hazards of biopsy in patients with malignant primary bone and soft tissue tumours. J. Bone Joint Surg. 1982, v. 64A, p. 1121-1127.
35. Musumeci R., Balzarini L., Ceglia E. et al. Soft tissue sarcomas. Imaging: an integrated approach. Ann. Oncol. 1992, v. 3, Suppl 2, p. 55-56.
36. O’Sullivan B., Davis A.M., Turcotte R. et al. Preoperative versus postoperative radiotherapy in soft_tissue sarcoma of the limbs: a randomised trial. Lancet. 2002, v. 359, p. 2235-2241.
37. Panicek D.M., Gatsonis C., Rosenthal D.I. et al. CT and MR imaging in the local staging of primary malignant musculoskeletal neoplasms: report of the Radiology Diagnostic Oncology Group. Radiology. 1997, v. 202, p. 237-246.
38. Pisters P.W.T., Leung D.H.Y, Woodruff J. et al. Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities. J. Clin. Oncol. 1996, v. 14 (5), p. 1679-1689.
39. Pollack A. Zagars G.K., Goswitz M.S., Liposarcoma: au- tcome and prognostic factors following conservation surgery and radiation therapy. Jnt. J. Radiat. Oncol. Biol. Phys. 1996, v. 36, No. 2, p. 34-39.
40. Poremba C. Soft tissue sarcomas: the role of histology and molecular pathology for differential diagnosis. Verh. Dtsch. Ges. Pathol. 2006, v. 90, p. 59-72.
41. Scoggins C.R., Pisters P.W. Diagnosis and management of soft tissue sarcomas. Adv. Surg. 2008, v. 42, p. 219-228.
42. Serpell J.W, Pitcher M.E. Pre-operative core biopsy of soft- tissue tumours facilitates their surgical management. Aust. N Z J Surg. 1998, v. 68 (12), p. 864.
43. Singer S. New diagnostic modalities in soft tissue sarcoma. Semin Surg Oncol. 1999, v. 17 (1), p. 11-22.
44. Taieb S., Ceugnart L., Gauthier H. et al. Soft tissue sarcoma: role of imaging for initial diagnosis and treatment Cancer. Radiother. 2006, v. 10 (1-2), p. 22-33.
45. Tateishi U., Hasegawa T., Yamamoto S. et al. Incidence of multiple primary malignancies in a cohort of adult patients with soft tissue sarcoma. Jpn. J. Clin. Oncol. 2005, v. 35, p. 444-452.
46. Ten Heuvel S.E., Hoekstra H.J., Suurmeijer A.J. Diagnostic accuracy of FISH and RT-PCR in 50 routinely processed synovial sarcomas. Appl. Immunohistochem Mol. Morphol. 2008, v. 16 (3), p. 246-250.
47. Totty W.G., Murphy W.A., Lee J.K.T. Soft-tissue tumors: MRimaging. Radiology. 1986, v. 160 (1), p. 135-141.
48. Trovik C.S., Bauer H.C., Alvegard T.A. et al. Surgical margins, local recurrence and metastasis in soft tissue sarcomas: 559 surgically-treated patients from the Scandinavian Sarcoma Group Register. 2000, v. 36 (6), p. 710-716.
49. Turc-Carel C, Pedeutour F, Durieux E Characteristic chromosome abnormalities and karyotype profiles in soft tissue tumors. Curr. Top. Pathol. 1995, v. 89, p. 73-94.
50. Ueda T, Aozasa K., Tsujimoto M. et al. Multivariate analysis for clinical prognostic factors in 163 patients with soft tissue sarcoma. Cancer (Phila). 1988, v. 62, p. 1444-1450.
51. Vanel D., Verstraete K.L., Shapeero L.G. Primary tumors of the musculoskeletal system. Radiol. Clin. N. Am. 1997, v. 35 (1), p. 213-237.
52. Verstraete K.L., Vanzieleghem B., DeDeene Y et al. Static, dynamic and first-pass MR imaging of musculoskeletal lesions using gadodiamide injection. Acta. Radiol. 1995, v. 36, p. 27-36.
53. Weeks R.G., Berquist T.H., McLeod R.A. et al. Magnetic resonance imaging of soft-tissue tumors: comparison with computed tomography. Magn. Reson. Imaging. 1985, v. 3, p. 345-352.
54. Weitz J., Antonescu C.R., Brennan M.F. Localized extremity soft tissue sarcoma: improved knowledge with unchanged survival over time. J. Clin. Oncol. 2003, v. 21, p. 2719-2725.
55. Windham T.C., Pisters P.W. Retroperitoneal sarcomas. Cancer. Control. 2005, v. 12 (1), p. 36-43.
56. Yang J.C., Chang A.E., Baker A.R. et al. Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity. J. Clin. Oncol. 1998, v. 16 (1), p. 197-203.
Review
For citations:
Burov D.A., Bokhyan B.Yu., Fedenko A.A., Khailenko V.A., Aliev M.D. Soft tissue sarcomas diagnostic mistakes. Bone and soft tissue sarcomas, tumors of the skin. 2009;(1):48-52. (In Russ.)
Views:
169
Email this article 
