Trabectedin in the treatment of soft tissue sarcomas: up to date data
https://doi.org/10.17650/2782-3687-2021-13-3-16-27
Abstract
Soft tissue sarcomas are a rare heterogeneous group of malignant tumors with mesenchymal nature. Soft tissue sarcomas accounts for less than 1 % of all cancers. Low efficiency of chemotherapy for soft tissue sarcomas, especially in advanced disease, is a burning issue. Trabectedin is one of the active agents approved for the treatment of advanced soft tissue sarcomas after the failure of standard chemotherapy. The article provides a literature review of the latest world-wide data of the effectiveness and role of trabectedin in the modern approach of soft tissue sarcomas treatment.
About the Authors
A. A. Fedenko
National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Russian Federation
3 2nd Botkinskiy Proezd, Moscow 125284, Russia
A. A. Tararykova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
Anastasia Alekseevna Tararykova
24 Kashirskoe Shosse, Moscow 115478, Russia
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For citations:
Fedenko A.A., Tararykova A.A. Trabectedin in the treatment of soft tissue sarcomas: up to date data. Bone and soft tissue sarcomas, tumors of the skin. 2021;13(3):16-26. (In Russ.) https://doi.org/10.17650/2782-3687-2021-13-3-16-27
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