Influence of resection width on the rate of local recurrence in combined treatment of soft tissues sarcomas
Abstract
Purpose. To evaluate the influence of resection width on the rate of local recurrence in patients with soft tissues sarcomas. Materials and methods. 30 patients (16 male, 14 female) were observed. The mean age was 44 years old. There were 14 (47%) patients with initial tumors, and 16 (53%) with local recurrence after the treatment. All patients receive neoadjuvant chemotherapy. Neoadjuvant radiation therapy was performed in 6 (19%) patients. All patients had surgical treatment done in time. The mean tumor volume was 1540 cm3. The adjuvant treatment was performed in 18 (69%) patients (chemotherapy inll, radiology in 4, both methods in 1 and surgical treatment of lungs metastasis in 2 patients). Results. The mean size of resection margins was 20mm. The mean follow up was 26 months. The local control rate was 87%. Disease free interval was 19 (63%), overall survival - 22 (73%). Resume. Combined method with radiology in treatment of patients with soft tissues sarcomas has specific advantages in a contrast with surgical treatment alone, and provides better disease free interval and overall survival.
About the Authors
V. V. Teplyakov
P.A. Hertcen Moscow Cancer Research Center
Russian Federation
Russian Federation
V. U. Karpenko
P.A. Hertcen Moscow Cancer Research Center
Russian Federation
Russian Federation
G. A. Frank
P.A. Hertcen Moscow Cancer Research Center
Russian Federation
Russian Federation
A. A. Bulanov
P.A. Hertcen Moscow Cancer Research Center
Russian Federation
Russian Federation
A. V. Bondarev
P.A. Hertcen Moscow Cancer Research Center
Russian Federation
Russian Federation
I. V. Droshneva
P.A. Hertcen Moscow Cancer Research Center
Russian Federation
Russian Federation
V. A. Derzhavin
P.A. Hertcen Moscow Cancer Research Center
Russian Federation
Russian Federation
A. V. Bukharov
P.A. Hertcen Moscow Cancer Research Center
Russian Federation
Russian Federation
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Review
For citations:
Teplyakov V.V., Karpenko V.U., Frank G.A., Bulanov A.A., Bondarev A.V., Droshneva I.V., Derzhavin V.A., Bukharov A.V. Influence of resection width on the rate of local recurrence in combined treatment of soft tissues sarcomas. Bone and soft tissue sarcomas, tumors of the skin. 2009;(1):28-33. (In Russ.)
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